Anogenital lichen sclerosus

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Pimecrolimus 1% cream for anogenital lichen sclerosus in childhood

BACKGROUND Lichen sclerosus is a chronic inflammatory disease with a predilection of the anogenital region. Because of the potential side effects of repeated local application of potent glucocorticosteroids, equally-effective, safer therapeutic options are required, especially in the treatment of children. CASE PRESENTATIONS We report on the efficacy of twice-daily application of pimecrolimus...

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Successful treatment of anogenital lichen sclerosus with topical tacrolimus.

BACKGROUND Lichen sclerosus of the anogenital area is a chronic inflammatory and fibrosclerotic disease associated with substantial morbidity. Topical ultrapotent corticosteroids are currently the treatment of choice. OBSERVATIONS Three prepubertal girls and 3 adults (2 men, 1 woman) were treated with 0.1% tacrolimus ointment once daily. All patients experienced complete resolution with long-...

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Anogenital lichen sclerosus: Change of tissue position as pathogenetic factor

•Lichen sclerosus in females primarily involves the hairless anogenital skin.•Skin tissue outside this area is constitutionally not at risk for lichen sclerosus.•Transplantation into the vulvar field may turn skin susceptible to lichen sclerosus.•Tissue inherent positional information might affect lichen sclerosus susceptibility.

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Constipation as a feature of anogenital lichen sclerosus in children.

OBJECTIVE To call attention to constipation as a frequent sign of lichen sclerosus (LS) in girls. METHODS A focused questionnaire was sent to parents of 24 girls with anogenital LS seen in the pediatric dermatology clinic at the Children's Hospital of Wisconsin between January 2001 and May 2004. RESULTS Eighteen of 24 questionnaires were completed and returned. The average age of onset of L...

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Extragenital bullous lichen sclerosus.

Lichen sclerosus is an inflammatory skin condition characterized by inflammation of the papillary dermis that leads to white scarlike plaques. It occurs classically in the genitals but also has extragenital manifestations with a variety of clinical presentations including a bullous variant. The purpose of this review is to characterize extragenital bullous lichen sclerosus, suggest that it may ...

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ژورنال

عنوان ژورنال: Indian Journal of Sexually Transmitted Diseases and AIDS

سال: 2020

ISSN: 2589-0557

DOI: 10.4103/ijstd.ijstd_49_17